基于栅极定义的量子点（QD）的量子计算机有望扩展。但是，随着量子位数量的增加，手动校准这些系统的负担变得不合理，必须使用自主调整。最近有一系列关于各种QD参数自动调整的演示，例如粗门范围，全局状态拓扑（例如，单QD，双QD），电荷和隧道与多种方法偶联。在这里，我们演示了一种直观，可靠和数据效率的工具集，用于自动化的全球状态和电荷调整，并在被认为是物理信息的调整（PIT）中。 PIT的第一个模块是一种基于动作的算法，该算法将机器学习（ML）分类器与物理知识相结合，以导航到目标全球状态。第二个模块使用一系列的一维测量值，首先清空电荷QD，然后校准电容式耦合，然后导航到目标电荷状态，从而调整目标电荷状态。基于动作的调整的成功率一致地超过了适合离线测试的模拟和实验数据的$ 95〜 \％$。使用模拟数据测试时，充电设置的成功率是可比性的，$ 95.5（5.4）〜\％$，对于离线实验测试的成功率略差，平均为$ 89.7（17.4）〜\％$（中位数$ 97.5） 〜\％$）。值得注意的是，高性能在学术清洁室和工业300毫米工艺线上制造的样品的数据中都得到了证明，进一步强调了坑的设备 - 不足程度。共同对一系列模拟和实验设备进行了这些测试，证明了PIT的有效性和鲁棒性。

量子点（QDS）阵列是一个有前途的候选系统，实现可扩展的耦合码头系统，并用作量子计算机的基本构建块。在这种半导体量子系统中，设备现在具有数十个，必须仔细地将系统仔细设置为单电子制度并实现良好的Qubit操作性能。必要点位置的映射和栅极电压的电荷提出了一个具有挑战性的经典控制问题。随着QD Qubits越来越多的QD Qubits，相关参数空间的增加充分以使启发式控制不可行。近年来，有一个相当大的努力自动化与机器学习（ML）技术相结合的基于脚本的算法。在这一讨论中，我们概述了QD器件控制自动化进展的全面概述，特别强调了在二维电子气体中形成的基于硅和GaAs的QD。将基于物理的型号与现代数值优化和ML相结合，证明在屈服高效，可扩展的控制方面已经证明非常有效。通过计算机科学和ML的理论，计算和实验努力的进一步整合，在推进半导体和量子计算平台方面具有巨大的潜力。

在Ultracold Atom实验中，数据通常以用于准备和测量系统的技术中固有的信息丢失的图像形式。当感兴趣的过程复杂时，这尤其成问题，例如Bose-Einstein缩合物中激发的相互作用（BECS）。在本文中，我们描述了一种与基于物理学的传统分析的机器学习（ML）模型的框架组合，以识别和跟踪BEC的图像中的多个Solitonic激发。我们使用基于ML的对象探测器来定位孤子激励并开发物理信息的分类器，将孤子激励分类为物理上积极的子类别。最后，我们介绍了一种质量指标量化特定特征是Kink Soliton的可能性。我们培训的此框架 - 焊接 - 焊接 - 被公开可作为开源Python包。焊接广泛适用于在合适的用户提供的数据集上培训时在寒冷原子图像中的特征识别。

当前的量子点（QD）设备的自动传动方法在显示出一些成功的同时，缺乏对数据可靠性的评估。当自主系统处理嘈杂或低质量数据时，这会导致意外的失败。在这项工作中，我们为QD设备的强大自动调整提供了一个框架，该QD设备将机器学习（ML）状态分类器与数据质量控制模块结合在一起。数据质量控制模块充当“守门人”系统，确保只有国家分类器处理可靠的数据。较低的数据质量会导致设备重新校准或终止。为了训练两个ML系统，我们通过结合QD实验的典型合成噪声来增强QD仿真。我们确认，在状态分类器的训练中包含合成噪声可以显着提高性能，在测试实验数据时，准确性为95.0（9）％。然后，我们通过表明状态分类器的性能随着预期的数据质量而恶化，从而验证数据质量控制模块的功能。我们的结果为嘈杂的QD设备的自动调整建立了强大而灵活的ML框架。

随着空间的尺寸增加，在真实数据中分类高维形状的问题在复杂性中增长。对于识别不同几何形状的凸形形状的情况，最近提出了一种新的分类框架，其中使用一种称为射线的一组一维表示的交叉点，其中具有形状的边界来识别特定几何形状。基于射线的分类（RBC）已经使用两维和三维形状的合成数据集进行了经验验证的（Zwolak等人。在第三讲习班关于机器学习和物理科学（Neurips 2020），温哥华，加拿大的第三次研讨会的程序中[ arxiv：2010年12月11日，2010年12月11日，最近也已经通过实验验证（Zwolak等，Prx量子2：020335,2021）。在这里，我们建立了由关键角度度量定义的形状分类所需的光线数量的绑定，用于任意凸形形状。对于两个维度，我们在形状的长度，直径和外部角度方面导出了射线数量的下限。对于$ \ mathbb {r} ^ n $的凸多台，我们将此结果概括为与二向角度的函数和多边形面的几何参数给出的类似绑定。该结果使得能够使用比体积或基于表面的方法基本更少的数据元素估计高维形状的不同方法。

Accurate determination of a small molecule candidate (ligand) binding pose in its target protein pocket is important for computer-aided drug discovery. Typical rigid-body docking methods ignore the pocket flexibility of protein, while the more accurate pose generation using molecular dynamics is hindered by slow protein dynamics. We develop a tiered tensor transform (3T) algorithm to rapidly generate diverse protein-ligand complex conformations for both pose and affinity estimation in drug screening, requiring neither machine learning training nor lengthy dynamics computation, while maintaining both coarse-grain-like coordinated protein dynamics and atomistic-level details of the complex pocket. The 3T conformation structures we generate are closer to experimental co-crystal structures than those generated by docking software, and more importantly achieve significantly higher accuracy in active ligand classification than traditional ensemble docking using hundreds of experimental protein conformations. 3T structure transformation is decoupled from the system physics, making future usage in other computational scientific domains possible.

Variational autoencoders model high-dimensional data by positing low-dimensional latent variables that are mapped through a flexible distribution parametrized by a neural network. Unfortunately, variational autoencoders often suffer from posterior collapse: the posterior of the latent variables is equal to its prior, rendering the variational autoencoder useless as a means to produce meaningful representations. Existing approaches to posterior collapse often attribute it to the use of neural networks or optimization issues due to variational approximation. In this paper, we consider posterior collapse as a problem of latent variable non-identifiability. We prove that the posterior collapses if and only if the latent variables are non-identifiable in the generative model. This fact implies that posterior collapse is not a phenomenon specific to the use of flexible distributions or approximate inference. Rather, it can occur in classical probabilistic models even with exact inference, which we also demonstrate. Based on these results, we propose a class of latent-identifiable variational autoencoders, deep generative models which enforce identifiability without sacrificing flexibility. This model class resolves the problem of latent variable non-identifiability by leveraging bijective Brenier maps and parameterizing them with input convex neural networks, without special variational inference objectives or optimization tricks. Across synthetic and real datasets, latent-identifiable variational autoencoders outperform existing methods in mitigating posterior collapse and providing meaningful representations of the data.

Differentiable Architecture Search (DARTS) has attracted considerable attention as a gradient-based Neural Architecture Search (NAS) method. Since the introduction of DARTS, there has been little work done on adapting the action space based on state-of-art architecture design principles for CNNs. In this work, we aim to address this gap by incrementally augmenting the DARTS search space with micro-design changes inspired by ConvNeXt and studying the trade-off between accuracy, evaluation layer count, and computational cost. To this end, we introduce the Pseudo-Inverted Bottleneck conv block intending to reduce the computational footprint of the inverted bottleneck block proposed in ConvNeXt. Our proposed architecture is much less sensitive to evaluation layer count and outperforms a DARTS network with similar size significantly, at layer counts as small as 2. Furthermore, with less layers, not only does it achieve higher accuracy with lower GMACs and parameter count, GradCAM comparisons show that our network is able to better detect distinctive features of target objects compared to DARTS.

Deep learning techniques with neural networks have been used effectively in computational fluid dynamics (CFD) to obtain solutions to nonlinear differential equations. This paper presents a physics-informed neural network (PINN) approach to solve the Blasius function. This method eliminates the process of changing the non-linear differential equation to an initial value problem. Also, it tackles the convergence issue arising in the conventional series solution. It is seen that this method produces results that are at par with the numerical and conventional methods. The solution is extended to the negative axis to show that PINNs capture the singularity of the function at $\eta=-5.69$

The Government of Kerala had increased the frequency of supply of free food kits owing to the pandemic, however, these items were static and not indicative of the personal preferences of the consumers. This paper conducts a comparative analysis of various clustering techniques on a scaled-down version of a real-world dataset obtained through a conjoint analysis-based survey. Clustering carried out by centroid-based methods such as k means is analyzed and the results are plotted along with SVD, and finally, a conclusion is reached as to which among the two is better. Once the clusters have been formulated, commodities are also decided upon for each cluster. Also, clustering is further enhanced by reassignment, based on a specific cluster loss threshold. Thus, the most efficacious clustering technique for designing a food kit tailored to the needs of individuals is finally obtained.